COMPARATIVE ANALYSIS OF ANTIMICROBIAL STRENGTH OF THREE MOST COMMON ANTIBIOTICS USED IN ENUGU

(CASE STUDY OF ANTIBIOTICS DRUGS BROUGHT IN OBIAGU)

By

OSAGIE IZEHIESE BEAUTY

Presented To

Science Technology Department

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ABSTRACT

In comparing the antimicrobial strength of three most common antibiotics, which includes: streptomycin chloranphenicol and gentarccin.

Samples of urine and high vaginal swab (H.V.S) were collected from park lane Enugu. The organisms isolated were pure culture of staphylococcus aureus and Escherichia coli

Sensitivity test was carried out with the use of sensitivity disk containing various minimum inhibitory concentration of the different antibiotics.

The result obtained shaved that gentamicn was more effective followed by chloramphenicol while some organisms shaved resistant to streptomycin.

LIST OF TABLE

TABLE 1 NUTRIENT AGAR

TABLE 2 BLOOD AGAR

TABLE 3: ANTIBIOTICS AGAINST SYAPHYLOCOCCUS AUREUS

TABLE 4: ANTIBIOTIC AGAINST ESCHERICHIA COLI

LIST OF FIGURES

FIGURE 1: STREPTOMYCIN

FIGURE 2: CHLORAMPHENICOL

FIGURE3: SENSITIVITY TEST ON STAPHYLOCOCCUS AUREUS

FIGURE 4 SENSITIVITY TEST ON ESCHERICHIA COLI

FIGURE 5: STAPHYLOCOCCUS AUREUS AGAINST ANTIBIOTICS

FIGURE 6: ESCHERICHIA COLI AGAINST ANTIBIOTICS

TABLE OF CONTENT

Title page

Certification

Dedication

Acknowledgement

Abstract

List of tables

List of figures

Table of contents

CHAPTER ONE

1.0 Introduction

1.1 Historical background

1.2 Aims and objective

1.3 Hypothesis

1.4 Statement of problem

1.5 Scope of study

1.6 Limitation of study

CHAPTER TWO

2.0 Literature review

3.1 Procurement of antibiotics

3.1.1 streptomycin

2.1.2 Chloramphenicol

2.1.3 Gentamicin

2.2 Antimicrobial activity in vitro

2.3 Antimicrobial activity in vivo

2.4 Resistance to antimicrobial drugs

2.5 Factors affecting antimicrobial activity

2.6 Clinical use of antibiotics

2.7 Characteristic of antibiotics

CHAPTER THREE

3.0 Materials and method

3.1 Sample collection

3.1.1 Media composition

3.1.2 Direction for the preparation of nutrient agar

3.1.3 Direction for the preparation of blood agar

3.1.4 Material used for the prewritten of media

CHAPTER FOUR

4.0 Isolation and identification procedures

4.1.1 Isolation and identification of staphylococcus aureus

4.1.2 Isolation and identification of escherichia coli

4.2 Sensitivity test

CHAPTER FIVE

5.0 RECOMMENDATION

5.1 CONCLUSION

REFERENCES

📄 Pages: 50 🧠 Words: 6572 📚 Chapters: 5 🗂️️ For: PROJECT

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