Rural development which is a component within the broader national development has remained a problem for both developed and developing countries. In order to achieve the desired rural development in the developing countries, there are proliferations of rural development strategies over the years, Nigeria inclusive. The objective of the study was to examine the effect of socio-economic infrastructure on rural development in Katsina State, Nigeria. The study chose three local governments as the geographical scope, while schools, electricity, market road healthcare infrastructures were the subject scope. The research population was 510,683, out of which 550 were taken as the sample size of the study using Saunders (2007) sampling method. A total of 520 questionnaires were returned both from the rural populace and staff respondents, and data was collected mainly through primary sources, while qualitative and quantitative methods of data analysis were employed. Regression analysis and correlation were used in testing the hypotheses postulated to establish the relationships between socio-economic infrastructure and rural development. Findings of the study indicated that, there is positive and significant relationship between provision of socio-economic infrastructure and rural development as all the five null hypotheses were rejected. The study recommends that, government should provide more socio-economic infrastructure in order to develop the rural areas.