This research work investigates the relationship between occupational self-concept and career interest among senior secondary school students in Suleja educational zone of Niger state. The study employed a correlational research design. The total of 310 senior secondary school students took part in the study: out of which 181 (58.4%) were males and 129 (41.6%) were females. Modified version of James Rounds Occupational Self-Concept scale (MVJROSCS) and Career Interest Inventory (CII) were used for data collection. Ten hypotheses were tested using Pearson Product Moment Correlation coefficient statistics at 0.05 level of significance. Results of the analysis indicated among other that significant positive relationship exist between outdooroccupational self-concept and outdoor career interest among senior secondary school students majoring in outdoor occupational environments. The results also shows that significant negative relationship exist between mechanical occupational self-concept and mechanical career interest among senior secondary school students majoring in mechanical occupational environments. Also, theresult revealed that significant negative relationship exist between artistic occupational self-concept and artistic career interest among senior secondary school students majoring in artistic occupational environments. Based on these findings, it was recommended among others that guidance counsellors and teachers should help to motivate and encourage students majoring in outdoor occupational environment that had positive correlation between their outdoor occupational self-concept and outdoor career interest.Guidance counsellors and teachers in secondary schools should help to improvemechanical occupational self-concept and mechanical career interest of students majoring in mechanical occupational environments by helping them see how mechanical occupational self-concept is connected to mechanical career interest during counselling and teaching. Also,Government and NGOs should collaborate with school guidance counsellors and organize programme such as Art Day or Art Week for secondary school studentsmajoring in artistic occupational environment and artists on different areas should be invited to exhibit their talents. This will assist them to promote their interest in art activities.