The aim of this study was to find out how prior knowledge of Drug addicts influences their perceptions on psychoactive substance abuse information communicated to them by NDLEA.In order to achieve the target of this study,six research questions were raised among which are; what are the prior Knowledge of Drug Addicts in Sabon Gari Metropolitan area of Kaduna State about the use of psychoactive substances and how do Drug Addicts in Sabon Gari Metropolitan area of Kaduna State perceive the psychoactive substance abuse information communicated by NDLEA. Relevant literature were reviewed on prior knowledge, perception, psychoactive substance abuse, psychoactive substance abuse information, research paradigm, social construction of reality, Chatman's theory of normative behaviour, previous studies that adopted theory of normative behavior.In order to have answers to the research questions raised, qualitative research methodology was adopted to answer the research questions through Snowball sampling techniques and face - to - face in-depth interview with 10 ex-rehabilitated Drug addicts in Sabon Gari metropolitan area of Kaduna state. Findings of this study revealed that prior knowledge of Drug Addicts about smoking; inhaling; swallowing; or drinking psychoactive substances are inner joy /happiness and source of energy to perform hard labor.Another finding of this study shows that Drug addicts perceived the information communicated to them by NDLEA positively as expected by the agency is because there are instances in the data collected from them that indicates their confessions about the usefulness of the information. Furthermore, some of the Drug addicts abuse were of the belief that the information was irrelevant to them because, there are instances in the data collected that indicates Drug addicts complains about how NDLEA officers treat them during their arrest and how they perceive NDLEA as corrupt agency which literally leads to negative perception about the information. The study concluded that there is a critical need for the management of NDLEA to be frequently and regularly train their staff on how to develop good relationship with the arrested and detained Drug Addicts under their custody. More importantly, community leaders in Sabon Gari Metropolitan area of Kaduna State should be frequently visiting Drug addicts that are under the custody of NDLEA in order to share their love to them. If this goal achieved it could serve as an avenue for changing the negative perceptions of Drug addicts about the psychoactive substance abuse information communicated to them by NDLEA.