ABSTRACT
The purpose of this study was to investigate ?Knowledge and Use of Psychoactive Substances among Undergraduate Students of Ahmadu Bello University, Zaria? Ex-post facto research design was used to study 327 subjects from twelve faculties of Ahmadu Bello University, Zaria. The subjects were drawn through stratified random sampling proportionate and convenient sampling techniques. A closed ended questionnaire type was used to obtain responses from the subjects. Data collected for this study were analysed using descriptive statistics of frequency, percentages and inferential statistics of chi square and t-test at 0.05 alpha level of significance. The findings showed that there was significant relationship between psychoactive substances use and age of the undergraduate students. Also, there was significant relationship between parental living (Alive) and psychoactive substance use among the undergraduate students of Ahmadu Bello University, Zaria. On the basis of the results, it was recommended that early health education on the effect of psychoactive substance use on the health of the students should commence before gaining admission into the University. Also, more awareness should be created on the ideal meaning and classification of psychoactive substance abuse and should be made available in learning courses, guidance and counseling centers. Those students' whose parents are dead became more prone to drug abuse, and should be given special counseling and attention by the authorities.